Regulation of smooth muscle profileration in hyperplastic arterial lesions
نویسندگان
چکیده
منابع مشابه
Regulation of contraction and relaxation in arterial smooth muscle.
Intracellular calcium concentration ([Ca2+]i)-dependent activation of myosin light chain kinase and its phosphorylation of the 20-kd light chain of myosin is generally considered the primary mechanism responsible for regulation of contractile force in arterial smooth muscle. However, recent data suggest that the relation between [Ca2+]i and myosin light chain phosphorylation is variable and dep...
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Regulation of rascuiar resistance is generally explained in terms of neural, hormonal, metabolic, and myogenic factors altering intracellular calcium [Ca] in vascular smooth muscle. Ca acts as a second messenger regulating the number of active crossbridges and force generation by binding to a myofilament regulatory protein. A search for the Ca-blndlng regulatory protein in arterial smooth muscl...
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The initiation of contractile force in arterial smooth muscle (SM) is believed to be regulated by the intracellular Ca2+ concentration and SM myosin type II phosphorylation. We tested the hypothesis that SM myosin type II operates as a molecular motor protein in electromechanical, but not in protein kinase C (PKC)-induced, contraction of small resistance-sized cerebral arteries. We utilized a S...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery
سال: 1989
ISSN: 0741-5214
DOI: 10.1016/0741-5214(89)90142-0